Viruses are then transferred to another person being bitten by an infected mosquito. Dengue is a common tropical infectious disease with a rising incidence among the indonesian population. Dengue is caused by four closely related viruses, commonly referred to as serotypes dengue 1, 2, 3, and 4. These symptoms could indicate a progression to dengue hemorrhagic fever, the severest form of the disease, with fatality rates as high as 20 percent. Dengue hemorrhagic fever can occur when someone is bitten by a mosquito or exposed to blood infected with the dengue virus. Symptoms typically begin three to fourteen days after infection. A flat, red rash may appear over most of the body 2 to 5 days after the fever starts.
Dengue is commonly confused with other infectious illnesses such as influenza, measles, malaria, typhoid, and scarlet fever. Dengue clinical manifestations include asymptomatic infections. Abstract dengue fever df is a major global health burden with a. Spatial and temporal patterns of dengue incidence in northeastern. It is a vasculopathy that consists in endothelial lesions which allow plasma leakage and hemorrhages. Dengue hemorrhagic is known as bonebreak fever, because in serious cases it literally feels as if your bones and joints are swollen and fractured.
Clinical implications and treatment of dengue core. In a small proportion of cases, the disease develops into severe dengue, also known as dengue. The viruses that cause dengue fever are related to those that. Export image and legend, or download trees as newick or phyloxml files for other. This increase is believed to be to be due to multiple factors. This increase is believed to be due to a combination of urbanization, population growth, increased international travel, and global warming. Dengue virus is a currently a problematic global infection. Known also as dengue hemorrhagic fever dhf, it starts abruptly with high continuous fever and headache plus respiratory and intestinal symptoms with sore throat, cough, nausea, vomiting, and abdominal pain. As of 2010 dengue fever is believed to infect 50 to 100 million people worldwide a year with 12 million lifethreatening infections. There are four different types of the dengue virus. Once you are infected with one of the viruses, you develop immunity to that virus for the rest of.
Dengue fever begins with a sudden high fever, often as high as 105 f 40. Todays topics arboviruses general concept dengue fever and dengue hemorrhagic fever mcqs and case studies 3. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. Dengue hemorrhagic fever medical definition merriam. Dengue hemorrhagic fever may arise from repeated infection with different serotypes of the dengue virus. Opinion 10 days of dengue fever the new york times. Viral hemorrhagic fever dengue fever presented by jega subramaniam, student guided by ap. Because the national center for global health and medicine is located close to the epicenter of this outbreak, 19 12% of the 160 cases of this outbreak were confirmed at this center.
Fatality is a distinct possibility only if the fever graduates to a more serious condition called the dengue hemorrhagic fever dhf. At the close of 2012, dengue fever, a band widely recognized for its trademark blend of 60s cambodian pop and psychedelic rock, proudly announced the launch. Clinical proteomics and cytokine profiling for dengue fever. Electronics, hindawi, sai, iet and a few national publishers. Viruses free fulltext exploiting the legacy of the arbovirus. It is caused by a bite from mosquitoes carrying dengue virus. Various species of aedesmosquitoes are vectors for the dengue virus and transmit the virus by biting a human host 3. This apparent gap is due to the disinvestment of training for the next generation of arbovirologists, which threatens to derail the rich history of virus discovery. Infection with one of these serotypes does not provide crossprotective immunity, so persons living in a dengueendemic area can have four dengue infections during their lifetimes.
More severe forms of the disease, dengue hemorrhagic fever or dengue shock syndrome are very rare among travelers. A second exposure to the virus can result in dengue hemorrhagic fever, a. Dhf starts abruptly with high continuous fever and headache plus respiratory and intestinal symptoms with sore throat, cough, nausea, vomiting, and abdominal pain. We report 19 cases of confirmed autochthonous dengue fever treated at the national center for global health and medicine in tokyo, japan, during august 26september 22, 2014 tables 1, 2. Her past medical history was limited to hypertension treated by lercanidipin and nebivolol. Pdf a framework for dengue surveillance and data collection in. Itll protect you from dengue fever, a virus spread through mosquito bites. Four related types of dengue viruses denv1, 2, 3 and 4 can cause dengue fever in majority of cases, the mosquito named aedes aegypti is responsible in the spread of the disease. Around the time the fever begins to subside usually 37 days after symptom onset, the patient may develop warning signs of severe disease. Each year, an estimated 100 million cases of dengue fever occur worldwide. Dengue fever is also known as backbone fever and the virus cannot be directly transmitted from one person to another. Guidelines for patient care in the region of the americas. Dengue fever is a mosquitoborne tropical disease caused by the dengue virus.
The classical form of dengue infection is manifested as high fever, violent headaches, thrombocytopenia, and hemoconcentration. Dengue fever is an acute viral infection characterized by fever. The illness may last up to 10 days, but complete recovery can take 2 to 4 weeks. Read more about symptoms, diagnosis, treatment, complications, causes and prognosis. Dengue fever is one of the most common tropical diseases worldwide. A framework for dengue surveillance and data collection in pakistan. Plasma proteome alterations in patients with df n 12 and dengue hemorrhagic fever dhf.
Untreated dengue fever has a mortality rate of about 5%. Clinical proteomics and cytokine profiling for dengue fever disease severity. A project always in constant evolution, exploring rhythms and sounds of the world. Dengue hemorrhagic fever and dengue shock syndrome some patients with dengue fever go on to develop dengue hemorrhagic fever dhf, a severe and sometimes fatal form of the disease. The disease shares some clinical signs with dengue, and.
For further information, including about cookie settings, please read our. Dengue fever is a disease spread by the aedes aegypti mosquito and caused by one of four dengue viruses that are closely related. The increasingly widespread distribution and the rising incidence of dengue virus infections are related to increased. Management of severe dengue hemorrhagic fever and bleeding.
Dengue fever nord national organization for rare disorders. It is felt that competent mosquito vectors are located in twentyeight of the fifty states. In 20, its annual incidence was reported to be 35 to 40100,000 with a mean age of above 15years old and a case fatality rate of 0. Its prevention dengue fever is a disease caused by viruses that are. The purpose of this study is to describe the care provided in a hydration tent, including early detection, treatment, and serial followup.
What is dengue hemorrhagic fever and dengue shock syndrome. Analysis of significant factors for dengue infection. Dengue is caused by four closely related viruses, commonly referred to as serotypes dengue1, 2, 3, and 4. Fatality is possible if dengue symptoms escalate to extremes.
It dramatically increased in frequency between 1960 and 2010, by 30 fold. Weather data were downloaded from the china meteorological data sharing. A 63yearold woman was admitted for acute chest pain and asthenia worsening for one week. Duane j gubler, dukenus graduate medical school, singapore, eng eong ooi, dukenus graduate medical school, singapore, goro kuno, arboviral disease branch, centers for disease control and prevention, subhash vasudevan, dukenus graduate medical school, singapore, jeremy farrar, wellcome trust, uk. Dengue fever and dengue hemorrhagic fever are reemerging diseases that are endemic in the tropics. Dhf dengue hemorrhagic fever medical meaning and pronunciation duration. Dengue fever, or west nile fever, is a mild viral illness transmitted by mosquitoes which causes fever, rashes and muscle and joint aches. A syndrome due to the dengue virus that tends to affect children under 10, causing abdominal pain, hemorrhage bleeding and circulatory collapse. At delhi, till 2003, the predominant serotype was dv2 genotype iv but in 2003 for the first time all four dengue virus subtypes were found to cocirculate in. Pdf dengue infection is a major cause of morbidity and mortality in.
Dengue and dengue hemorrhagic fever linkedin slideshare. Early detection of the disease, followed by intravenous fluid therapy in patients with dengue hemorrhagic fever dhf or with warning signs of dengue has a major impact on the prognosis. Disease burden of dengue fever and dengue haemorrhagic fever 3. Affordable and search from millions of royalty free images, photos and vectors. The 37yearold actor was first hospitalized two weeks ago with dengue hemorrhagic fever that at one point put him in a coma.
Acute pericarditis after dengue fever sciencedirect. Dengue fever is caused by virus that is transmitted when a specific type of mosquito bites humans. Infection with one serotype elicits lifelong immunity, but only to that serotype and there is evidence that subsequent infection with another serotype increases the chance of developing dengue hemorrhagic fever or dengue shock syndrome. There are several mosquitoes in the tropic areas that are carriers of the dengue virus and this mosquito can also be infected if it bites any person who has dengue virus in his blood. Dengue and dengue hemorrhagic fever dhf are caused by one of four closely related, but antigenically distinct, virus serotypes den1, den2, den3, and den4, of the genus flavivirus. Dengue is a prevalent arthropodborne viral disease in tropical and subtropical areas of the globe. Por sahawong update, dengue in thailand outbreak news today. Treatment includes rehydration and recovery is expected. Diagnosis via new molecularbased techniques have become a new hope for early diagnosis, but are still limited due to their costs and. Dengue and dengue hemorrhagic fever in the americas, guidelines for.
There is no effective treatment for dengue and vaccination, so far, offers. Dengue brings a triad of distress signals which include fever, pain and skin rash, but the majority of people infected manage to stave off the worst side effects within days of its onset. Autochthonous dengue fever, tokyo, japan, 2014 volume 21. Transmission aedes aegypti is the main mosquito vector that transmits the dengue virus from person to person. Esse video devidamente registrado, esta a venda juntamen. The reasons for this resurgence and emergence of dengue hemorrhagic fever in the waning years of the 20th century are complex and not fully understood, but. Dengue fever and dengue hemorrhagic fever dhf are acute febrile diseases transmitted by mosquitoes, which occur in the tropics, can be lifethreatening, and are caused by four closely related. Searchable database of dengue virus genomes with visualization and. The aedes aegypti mosquito is mostly found in tropical areas including subcontinent, pakistan, africa and latin. A case of dengue hemorrhagic fever and the use of supportive therapy aishah ali, md, emily sutton, md introduction dengue fever is a mosquitobound viral illness that occurs in tropical climates.